A former oncology professor with Roswell Park’s Cancer institute, Mikhail Blagosklonny works as a scientist specializing in studies on aging and also cancer. He holds an internal medicine doctorate and a Cardiology and Experimental medicine PhD from St. Petersburg’s Pavlor medical university. Prior to that, he was also an associate professor at New York’s medical college before moving to Albany as a senior scientist with Ordway’s Research institute. Mikhail Blagosklonny proposed the use of a cancer drug, rapamycin as a way of life extension method in his hypothesis on the role played by TOR signaling in both cancer and also aging. He also works as an editor for medical magazines and as a medical writer.
Rapamycin is a drug used in prevention of organ transplant rejection and also used in treatment of lung diseases that’s rare; it is also used to coat coronary stents. Rapamycin has great immunosuppressive and good ant proliferative properties. Dr. Blagosklonny is known for his research and advocacy for use of the drug to prolong human life spans.
Qualities of rapamycin
While other immunosuppressive drugs affect the kidneys adversely, rapamycin’s toxicity levels towards kidneys are low.
Treatment of hemolytic uremic syndrome:
The same low toxicity towards kidneys is the reason it is also used to treat this rare disease that is a concoction of kidney failure, little platelet count and anemia whose corrective measure is a kidney transplant, a process that might have the transplanted kidney contract the same disease, a situation the drug prevents.
Its ant- proliferative properties makes rapamycin capable of enhancing the body’s immune response capacities against tumors, promoting tumor regression in the process, thereby reducing risks for cancer patients who need organ transplants.
Rapamycin is used in coating coronary stents to prevent re-stenosis occurrence in arteries after a balloon angioplasty procedure, this ensures one does not need to repeat the procedure.
Tuberous Sclerosis Complex (TSC) Treatment:
This is a disorder that causes tumor growth in areas such as the brain and kidneys as well as other organs in the body. Rapamycin helps suppress growth of TSC in both children and adults.
Plans for oncology
Mikhail Blagosklonny is interested in knowing the connection between cancer and aging and to see if there is a reason behind cancer being common among the senior citizens and hopes to find a way of effectively treating cancer in an inexpensive and less painful manner than it is currently done, he hopes to achieve this by finding a way to identify and eliminate cancerous cells without destroying cells that are needed in mind and body recovery after months or years of undergoing cancer treatment.
On aging, he has carried out tests on mice and also humans, with results showing elderly patients experiencing rejuvenation in immunity after getting a dose of Rapamycin before vaccination. However, this is not conclusive proof that the drug increases human life. Mikhail exudes experience when it comes to scientific research.